Cervical length in uncomplicated pregnancy: A study of sociodemographic predictors of cervical changes across gestation

Am J Obstet Gynecol. 1999 Mar;180(3 Pt 1):639-44. doi: 10.1016/s0002-9378(99)70267-x.

Abstract

Objective: We conducted this study to evaluate sociodemographic factors associated with changes in the length of the cervix across gestation in pregnancies that resulted in term deliveries.

Study design: This study is an observational cohort design of sonographically determined cervical length measured at 3- to 4-week intervals in 125 women with a singleton pregnancy between 20 and 32 weeks gestation. We developed a structured questionnaire to collect psychosocial and sociodemographic characteristics. We used bivariate analysis, analysis of variance, and regression analysis to study variation in cervical length.

Results: Overall, cervical length decreased minimally as gestational age progressed. However, among black women cervical length decreased significantly with increasing gestational age (P =.006). In addition, high psychosocial stress was associated with significantly shorter cervices later in gestation, independent of race (P =.003). Finally, women whose occupations involved skilled manual labor had shorter cervices (P =.02).

Conclusions: Women who are black, under stress, or working as skilled manual laborers demonstrate significant shortening of the cervix during gestation. Given that a shorter cervix predisposes to preterm delivery, our findings provide new insights into the well-described association of these psychosocial and sociodemographic factors with an increased risk of preterm delivery.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Black People / genetics
  • Black or African American
  • Cervix Uteri / diagnostic imaging*
  • Cohort Studies
  • Female
  • Humans
  • Obstetric Labor, Premature / ethnology
  • Obstetric Labor, Premature / etiology*
  • Obstetric Labor, Premature / genetics
  • Occupations
  • Pregnancy / ethnology
  • Pregnancy / physiology*
  • Prospective Studies
  • Socioeconomic Factors
  • Stress, Psychological / complications
  • Surveys and Questionnaires
  • Ultrasonography