Transduction of dendritic cells with adenoviral vectors encoding CTLA4-Ig markedly reduces their allostimulatory activity

Transplant Proc. 1999 Feb-Mar;31(1-2):797. doi: 10.1016/s0041-1345(98)01774-6.

Authors

L Lu¹, W C Lee, A Gambotto, C Zhong, P D Robbins, S Qian, J J Fung, A W Thomson

Affiliation

¹ Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pennsylvania, USA.

PMID: 10083343
DOI: 10.1016/s0041-1345(98)01774-6

No abstract available

MeSH terms

Abatacept
Adenoviridae
Animals
Antigens, CD
Antigens, Differentiation / genetics
Antigens, Differentiation / physiology*
Bone Marrow Cells / cytology
Bone Marrow Cells / immunology
CTLA-4 Antigen
Cells, Cultured
Dendritic Cells / cytology
Dendritic Cells / drug effects
Dendritic Cells / immunology*
Genetic Vectors
Granulocyte-Macrophage Colony-Stimulating Factor / pharmacology
Green Fluorescent Proteins
Immunoconjugates*
Interleukin-4 / pharmacology
Luminescent Proteins / genetics
Lymphocyte Activation
Mice
Mice, Inbred C3H
Mice, Inbred Strains
Recombinant Fusion Proteins / immunology
T-Lymphocytes / immunology*
T-Lymphocytes, Cytotoxic / immunology
Transfection
beta-Galactosidase / genetics

Substances

Antigens, CD
Antigens, Differentiation
CTLA-4 Antigen
Ctla4 protein, mouse
Immunoconjugates
Luminescent Proteins
Recombinant Fusion Proteins
Green Fluorescent Proteins
Interleukin-4
Abatacept
Granulocyte-Macrophage Colony-Stimulating Factor
beta-Galactosidase