An improved method for gas chromatographic determination of urinary xylitol and glucuronic, glucaric gulonic and ascorbic acids, with their values in the rat, rabbit, guinea-pig and marmoset

Xenobiotica. 1978 Oct;8(10):605-9. doi: 10.3109/00498257809069572.

Abstract

1. Urinary levels of xylitol and glucuronic, glucaric, gulonic and ascorbic acids were measured in the rat, rabbit, guinea-pig and marmoset by an improved g.l.c. technique. 2. Administration of a compound (2-methylbenzanilide) known to be conjugated and excreted as a beta-glucuronide had some effect on the output of these compounds of the glucuronic acid pathway in all four species, and caused a significant decrease in gulonic acid in the rat.

MeSH terms

  • Animals
  • Ascorbic Acid / urine*
  • Callitrichinae
  • Chromatography, Gas / methods
  • Female
  • Glucaric Acid / urine*
  • Glucuronates / urine*
  • Guinea Pigs
  • Haplorhini
  • Male
  • Rabbits
  • Rats
  • Species Specificity
  • Sugar Acids / urine*
  • Time Factors
  • Xylitol / urine*

Substances

  • Glucuronates
  • Sugar Acids
  • gulonic acid
  • Ascorbic Acid
  • Glucaric Acid
  • Xylitol