Acute renal failure requiring haemodialysis after high doses percutaneous acetic acid injection for hepatocellular carcinoma

Acta Gastroenterol Belg. 1999 Jan-Mar;62(1):49-51.

Abstract

Recently, ultrasound-guided percutaneous acetic acid injection has been proposed in the treatment of hepatocellular carcinoma as an alternative to percutaneous ethanol injection. We report the case of severe renal failure requiring haemodialysis which occurred in a patient with 4 cm hepatocellular carcinoma treated adequately by high dose percutaneous acetic acid injection. The risk of such a serious side effect, likely related to a direct toxic effect of acetic acid, should be of concern when considering percutaneous treatment of hepatocellular carcinoma. Acute renal failure has been reported as a complication of acetic acid poisoning, but to our knowledge, we report here the first case of acute renal failure following high dose percutaneous acetic acid injection.

Publication types

  • Case Reports

MeSH terms

  • Acetic Acid / administration & dosage
  • Acetic Acid / adverse effects*
  • Acute Kidney Injury / chemically induced
  • Acute Kidney Injury / therapy*
  • Aged
  • Carcinoma, Hepatocellular / therapy*
  • Humans
  • Injections, Intralesional
  • Liver Neoplasms / therapy*
  • Male
  • Renal Dialysis*

Substances

  • Acetic Acid