Abstract
Mupirocin is a topical antimicrobial agent that has been successfully used to eradicate methicillin-resistant Staphylococcus aureus from the anterior nares and other sites of patients and health care personnel. This report describes the acquisition of a novel mupirocin resistance gene (ileS) by an epidemic MRSA clone that is geographically widespread in Brazil.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anti-Bacterial Agents / pharmacology*
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Brazil
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Cross Infection / microbiology
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DNA, Bacterial / analysis
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Disease Outbreaks
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Drug Resistance, Microbial / genetics*
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Drug Resistance, Multiple
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Humans
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Methicillin Resistance
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Microbial Sensitivity Tests
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Mupirocin / pharmacology*
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Physical Chromosome Mapping
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Staphylococcal Infections / microbiology*
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / genetics
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Staphylococcus aureus / isolation & purification
Substances
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Anti-Bacterial Agents
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DNA, Bacterial
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Mupirocin