Structure of NG-061, a novel potentiator of nerve growth factor (NGF) isolated from Penicillium minioluteum F-4627

R Bhandari; T Eguchi; A Sekine; Y Ohashi; K Kakinuma; M Ito; K Mizoue

doi:10.7164/antibiotics.52.231

Structure of NG-061, a novel potentiator of nerve growth factor (NGF) isolated from Penicillium minioluteum F-4627

J Antibiot (Tokyo). 1999 Mar;52(3):231-4. doi: 10.7164/antibiotics.52.231.

Authors

R Bhandari¹, T Eguchi, A Sekine, Y Ohashi, K Kakinuma, M Ito, K Mizoue

Affiliation

¹ Department of Chemistry, Tokyo Institute of Technology, Japan.

PMID: 10348037
DOI: 10.7164/antibiotics.52.231

Abstract

The structure of NG-061, a new potentiator of nerve growth factor (NGF) isolated from Penicillium minioluteum F-4627, was determined by spectroscopic analysis and X-ray diffraction method to be phenylacetic acid 2-(2-methoxy-4-oxocyclohexa-2,4-dienylidene)-hydrazide.

MeSH terms

Chromatography, High Pressure Liquid
Hydrazines / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Nerve Growth Factors / chemistry*
Penicillium / chemistry*
Phenylacetates / chemistry*
X-Ray Diffraction

Substances

Hydrazines
NG 061
Nerve Growth Factors
Phenylacetates