We present the case of an 60-year-old male patient that after a acute myocardial infarction inferior diagnostic was subjected to a fibrinolysis with streptokinase. The evolution from the cardiologic point of view was favourable, but at fourth day postacute myocardial infartion he starts with peripherics vasculars symptoms, pain and livedo reticularis in lower part of the body. A symptomatic treatment was made requiring amputation of his fifth right toe. The evolution was towards healing without any organic afectation at another level.