Normal urodynamics in patients with bladder exstrophy: are they achievable?

J Urol. 1999 Sep;162(3 Pt 1):841-4; discussion 844-5. doi: 10.1097/00005392-199909010-00072.

Abstract

Purpose: Urodynamic study was performed in patients with exstrophy to determine the effect of bladder neck reconstruction and the ability to achieve normal urodynamics following surgery.

Materials and methods: A total of 30 exstrophy cases at different stages of reconstruction were retrospectively reviewed in terms of bladder capacity, compliance, stability and presence of detrusor contractions following urodynamic study.

Results: Bladder capacity increased from a third predicted volume for age to half after reconstruction. Approximately 80% of patients had compliant and stable bladders before bladder neck reconstruction. Following bladder neck reconstruction approximately half of the patients maintained normal compliance with a smaller number maintaining normal stability. A quarter of patients maintained normal filling dynamics following bladder neck reconstruction, and 19% maintained normal filling and voiding dynamics after reconstruction.

Conclusions: The majority of closed exstrophy bladders have normal filling dynamics before bladder neck reconstruction. Compliance and stability are impaired following bladder neck reconstruction. Approximately 25% of patients with exstrophy may maintain normal detrusor function following reconstruction. However, less invasive alternatives to the Young-Dees-Leadbetter bladder neck reconstruction should be sought.

MeSH terms

  • Adolescent
  • Bladder Exstrophy / physiopathology*
  • Bladder Exstrophy / surgery*
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Male
  • Postoperative Care
  • Preoperative Care
  • Retrospective Studies
  • Sex Factors
  • Urodynamics*
  • Urologic Surgical Procedures