[Ventricular tachycardia after erythromycin administration in a newborn with congenital AV-block]

Klin Padiatr. 1999 Nov-Dec;211(6):465-8. doi: 10.1055/s-2008-1043836.
[Article in German]

Abstract

This report is on a newborn with congenital complete av-block due to a maternal collagenosis. The intravenous application of erythromycin produced premature ventricular beats and non sustained ventricular tachycardias by prolongation of the QT interval. After discontinuation of the erythromycin application, the QT-interval normalised.

Conclusion: In atrioventricular conduction disorders with severe bradycardia and prolongation of the QT interval, the application of erythromycin--if unavoidable--should be managed by slow intravenous infusion and with permanent ECG monitoring.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects*
  • Electrocardiography
  • Erythromycin / administration & dosage
  • Erythromycin / adverse effects*
  • Heart Block / complications*
  • Heart Block / congenital*
  • Heart Block / physiopathology
  • Humans
  • Infant, Newborn
  • Infusions, Intravenous
  • Injections, Intravenous
  • Male
  • Sepsis / complications
  • Sepsis / drug therapy*
  • Tachycardia, Ventricular / chemically induced*
  • Tachycardia, Ventricular / physiopathology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Erythromycin