Medical management of eosinophilic granuloma of the cervical spine

Pediatr Neurosurg. 1999 Sep;31(3):159-62. doi: 10.1159/000028853.

Abstract

We report a case of eosinophilic granuloma involving the vertebral bodies of the cervical spine in a 33-month-old girl. This lesion was diagnosed by needle biopsy and treated with prednisone and vinblastine therapy along with immobilization in a Minerva brace. The child has done well over a 9-month follow-up and has shown MRI evidence of resolution of the lesion, reestablishment of structural integrity within the cervical spine and potential reconstitution of the involved vertebral bodies.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage*
  • Antineoplastic Agents, Phytogenic / administration & dosage*
  • Biopsy, Needle
  • Braces
  • Cervical Vertebrae* / pathology
  • Child, Preschool
  • Drug Therapy, Combination
  • Eosinophilic Granuloma / drug therapy*
  • Eosinophilic Granuloma / pathology
  • Female
  • Follow-Up Studies
  • Humans
  • Magnetic Resonance Imaging
  • Prednisone / administration & dosage*
  • Spinal Diseases / drug therapy*
  • Spinal Diseases / pathology
  • Vinblastine / administration & dosage*

Substances

  • Anti-Inflammatory Agents
  • Antineoplastic Agents, Phytogenic
  • Vinblastine
  • Prednisone