The role of histone H1 in chromatin condensation and transcriptional repression

Genetica. 1999;106(1-2):117-24. doi: 10.1023/a:1003745315540.

Abstract

Linker histones are a major determinant of chromatin condensation. We discuss here the nature and position of the interaction of the globular domain of histone H5 with the core nucleosome and the relevance of this positioning to chromatin structure and the regulation of transcription of the Xenopus borealis 5S rRNA genes.

Publication types

  • Review

MeSH terms

  • Animals
  • Chromatin / chemistry
  • Chromatin / genetics
  • Chromatin / metabolism*
  • Histones / chemistry
  • Histones / metabolism*
  • Models, Genetic
  • Models, Molecular
  • Nucleosomes / chemistry
  • Nucleosomes / metabolism
  • RNA, Ribosomal, 5S / chemistry
  • RNA, Ribosomal, 5S / metabolism
  • Transcription, Genetic*
  • Xenopus

Substances

  • Chromatin
  • Histones
  • Nucleosomes
  • RNA, Ribosomal, 5S