Prevalence of autoantibodies against contractile proteins in coronary artery disease and their clinical implications

Am J Cardiol. 2000 Apr 1;85(7):870-2, A6, A9. doi: 10.1016/s0002-9149(99)00883-8.

Abstract

In this initial study, we found that autoantibodies against actin and myosin were present during and after an acute coronary syndrome. Moreover, they correlated with persistent troponin-I elevation at follow-up, and with late myocardial infarction.

Publication types

  • Comparative Study
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Actins / immunology*
  • Acute Disease
  • Autoantibodies / analysis*
  • Biomarkers / blood
  • Coronary Disease / blood
  • Coronary Disease / immunology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myosins / immunology*
  • Prevalence
  • Prognosis
  • Troponin I / immunology*

Substances

  • Actins
  • Autoantibodies
  • Biomarkers
  • Troponin I
  • Myosins