A new catalytic and enantioselective desymmetrization of symmetrical methylidene cycloalkene oxides

F Bertozzi; P Crotti; F Macchia; M Pineschi; A Arnold; BL Feringa

doi:10.1021/ol005584o

A new catalytic and enantioselective desymmetrization of symmetrical methylidene cycloalkene oxides

Org Lett. 2000 Apr 6;2(7):933-6. doi: 10.1021/ol005584o.

Authors

F Bertozzi¹, P Crotti, F Macchia, M Pineschi, A Arnold, BL Feringa

Affiliation

¹ Dipartimento di Chimica Bioorganica e Biofarmacia, Universita di Pisa, Italy.

PMID: 10768190
DOI: 10.1021/ol005584o

Abstract

Chiral copper complexes of C2-symmetrical phosphoroamidites were found to be highly effective catalysts for both kinetic resolution and novel desymmetrization reactions of new methylidene epoxycycloalkanes.