A satellite DNA containing CENP-B box-like motifs is present in the antarctic scallop Adamussium colbecki

Gene. 2000 Apr 18;247(1-2):175-80. doi: 10.1016/s0378-1119(00)00101-3.

Abstract

The DNA of the Antarctic scallop Adamussium colbecki was found to contain a highly repeated sequence identifiable upon restriction with endonuclease BglII. The monomeric unit - denominated pACS (about 170bp long) - was cloned. Southern blot hybridization yielded a ladder-like banding pattern, indicating that the repeated elements are tandemly arranged in the genome and therefore represent a sequence of satellite DNA. Sequence analysis of five different clones revealed the presence of various subfamilies, some of which showed a high degree of divergence. In each clone, regions homologous to the mammalian CENP-B box were observed. A region homologous to the CDEIII centromeric sequence of yeast was also found in one of the clones. These observations suggest a relationship of the pACS family to the centromeric area in A. colbecki.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antarctic Regions
  • Autoantigens*
  • Base Sequence
  • Binding Sites
  • Blotting, Southern
  • Centromere Protein B
  • Chromosomal Proteins, Non-Histone / metabolism*
  • DNA / chemistry
  • DNA / genetics
  • DNA, Satellite / genetics*
  • DNA, Satellite / metabolism
  • DNA-Binding Proteins*
  • Molecular Sequence Data
  • Mollusca / genetics*
  • Sequence Alignment
  • Sequence Analysis, DNA
  • Sequence Homology, Nucleic Acid

Substances

  • Autoantigens
  • Centromere Protein B
  • Chromosomal Proteins, Non-Histone
  • DNA, Satellite
  • DNA-Binding Proteins
  • DNA

Associated data

  • GENBANK/AJ286808
  • GENBANK/AJ286809
  • GENBANK/AJ286810
  • GENBANK/AJ286811
  • GENBANK/AJ286812