Getting to the point with myosin VI

Curr Biol. 2000 Apr 20;10(8):R294-7. doi: 10.1016/s0960-9822(00)00433-4.

Abstract

The recent observation that class VI myosins move in a direction opposite to all other known myosins, taken together with analyses of mutant flies and mice, suggests that, instead of moving vesicles out towards the cell periphery, myosin VI more likely brings materials or membranes into the cell.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Actins / metabolism
  • Animals
  • Cell Line
  • Cell Polarity
  • Cytoskeleton / physiology*
  • Drosophila
  • Mice
  • Mice, Mutant Strains
  • Molecular Motor Proteins / physiology*
  • Mutation
  • Myofibrils / physiology
  • Myosin Heavy Chains / physiology*

Substances

  • Actins
  • Molecular Motor Proteins
  • myosin VI
  • Myosin Heavy Chains