Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos n. species

J S Simpson; M J Garson; J W Blunt; M H Munro; J N Hooper

doi:10.1021/np990431z

Mycalamides C and D, cytotoxic compounds from the marine sponge Stylinos n. species

J Nat Prod. 2000 May;63(5):704-6. doi: 10.1021/np990431z.

Authors

J S Simpson¹, M J Garson, J W Blunt, M H Munro, J N Hooper

Affiliation

¹ Department of Chemistry, The University of Queensland, Brisbane, Queensland 4072, Australia.

PMID: 10843596
DOI: 10.1021/np990431z

Abstract

The new cytotoxic compounds, mycalamides C (3) and D (4), have been isolated from the marine sponge Stylinos n. sp., along with the known theopederin E (1) and mycalamide A (2).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Antineoplastic Agents / isolation & purification*
Antineoplastic Agents / pharmacology
Leukemia P388 / drug therapy
Magnetic Resonance Spectroscopy
Optical Rotation
Porifera / chemistry*
Pyrans / isolation & purification*
Pyrans / pharmacology
Tumor Cells, Cultured

Substances

Antineoplastic Agents
Pyrans
mycalamide C
mycalamide D