A 62 year-old man had been suffered from headache and left shoulder pain since March 1997. In November 1997, he visited our hospital complaining of work incapability, slow-moving and somnolence. Multiple nodular lesions were found in his brain and abdominal wall. Biopsy of the abdominal wall mass revealed small cell carcinoma/neuroendocrine cell carcinoma. Radiation therapy on brain and abdominal wall was done and these tumor nodules became decreased. However, recurrence and metastasis occurred later and died at March 1998. The autopsy revealed the origin of these tumors was the prostate. The prostatic tumors revealed neuroendocrine cell carcinoma mainly, combining a portion of adenocarcinoma. Most parts of the metastatic tumors were neuroendocrine cell carcinoma. Only the seventh thoracic vertebral metastasis was bone-sclerosing metastasis of adenocarcinoma.