Detecting hypermutations in viral sequences with an emphasis on G --> A hypermutation

P P Rose; B T Korber

doi:10.1093/bioinformatics/16.4.400

Detecting hypermutations in viral sequences with an emphasis on G --> A hypermutation

Bioinformatics. 2000 Apr;16(4):400-1. doi: 10.1093/bioinformatics/16.4.400.

Authors

P P Rose¹, B T Korber

Affiliation

¹ Theoretical Biology and Biophysics, Los Alamos National Laboratories, MS K710 Los Alamos, NM 87544, USA. pxr@t10.lanl.gov

PMID: 10869039
DOI: 10.1093/bioinformatics/16.4.400

Abstract

Summary: This program compares sequence sets to a reference sequence, tallies G --> A hypermutations, and presents the results in various tables and graphs, which include dinucleotide context, summaries of all observed nucleotide changes, and stop codons introduced by hypermutation.

Availability: www.hiv.lanl.gov/HYPERMUT/hypermut.html

Publication types

Research Support, U.S. Gov't, Non-P.H.S.
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Adenine*
Animals
Guanine*
Humans
Point Mutation*
Software*
Viruses / genetics*

Substances

Guanine
Adenine