Complications of photodynamic therapy in gastrointestinal disease

Gastrointest Endosc Clin N Am. 2000 Jul;10(3):487-95.

Abstract

The primary complications of photodynamic therapy of the esophagus include cutaneous photosensitivity and esophageal strictures. Atrial fibrillation and pleural effusion have been reported but appear to be rare or not clinically significant. Cutaneous photosensitivity can be minimized if the adequate precautions are taken to protect patients from sunlight exposure. Stricture formation may be decreased by proper dosimetry and avoiding multiple overlapping light applications.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Chest Pain / etiology*
  • Endoscopy, Gastrointestinal / adverse effects
  • Esophageal Stenosis / etiology
  • Gastrointestinal Diseases / drug therapy*
  • Gastrointestinal Diseases / pathology
  • Gastrointestinal Hemorrhage / etiology
  • Humans
  • Intestinal Mucosa / drug effects
  • Intestinal Mucosa / pathology
  • Photochemotherapy / adverse effects*
  • Photochemotherapy / methods
  • Photosensitizing Agents / adverse effects*
  • Pleural Effusion / etiology*

Substances

  • Photosensitizing Agents