A developmental view of the effects of an energy and micronutrient supplement in undernourished children in Indonesia

Eur J Clin Nutr. 2000 May:54 Suppl 2:S107-13. doi: 10.1038/sj.ejcn.1601012.

Abstract

Objectives: This paper presents the results of a structural equation model testing whether the longitudinal data of the Pangalengan subjects fit the theoretical model regarding the intellectual delay of undernourished children.

Design: Two cohorts of children were randomly assigned to three treatments: E = 1171 kJ + 12 mg iron; M = 12 mg iron + 209 kJ; S = 104 kJ. Supplementation was given for 6 months.

Setting: The sites were six tea plantations in Indonesia.

Subjects: A 12-month-old (n = 53) and an 18-month-old (n = 83) cohort were recruited from day-care-centers. Inclusion criteria were: no chronic disease; length-for-age = < 1 standard deviation (s.d.) and weight-for-length between -1 and -2 s.d. of the median of the reference of the World Health Organization.

Methods: Twenty-four-hour dietary intakes were assessed using the weighted individual inventory technique. Body weight and length were obtained using standard procedures; motor development was assessed with the Bayley Scale and with a custom made scale for motor development leading to bipedal locomotion. Four-hour observations were made of the child's interactions with the environment. Carrying a child in the arms and exploratory behavior were used as indicators of caregiving and exploration. All measurements were obtained every 2 months.

Results: The original model did not fit the data. The model was then modified with the inclusion of two new pathways: from activity and from motor development to mental development. Following these adjustments the model fit the data for each cohort and for both cohorts combined.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthropometry
  • Brain / growth & development
  • Child Development*
  • Cognition
  • Cohort Studies
  • Diet Records
  • Dietary Supplements*
  • Energy Intake / physiology*
  • Female
  • Humans
  • Indonesia
  • Infant
  • Infant Nutritional Physiological Phenomena*
  • Locomotion
  • Longitudinal Studies
  • Male
  • Micronutrients / administration & dosage*
  • Micronutrients / pharmacology
  • Models, Biological
  • Nutrition Disorders / diet therapy
  • Nutrition Disorders / physiopathology*

Substances

  • Micronutrients