Bone sarcoidosis

Curr Opin Rheumatol. 2000 Jul;12(4):321-30. doi: 10.1097/00002281-200007000-00016.

Abstract

Sarcoidosis is a disease that exhibits extremely heterogeneous clinical manifestations. Although the lungs are the most commonly involved organs, the extension of the granulomatous process may also affect the bones. Almost any bone can be involved; curiously, the small bones of the hands and feet are most frequently affected. Diagnosis and recognition of osseous sarcoidosis is easy, but the therapy is disappointing. Corticosteroids and antimalarials may control pain and swelling, but usually do not influence the course of osseous sarcoidosis.

Publication types

  • Review

MeSH terms

  • Antimalarials / therapeutic use
  • Bone Diseases* / diagnostic imaging
  • Bone Diseases* / drug therapy
  • Bone Diseases* / etiology
  • Bone Diseases* / pathology
  • Chloroquine / therapeutic use
  • Female
  • Glucocorticoids / therapeutic use
  • Granuloma / pathology
  • Humans
  • Hydroxychloroquine / therapeutic use
  • Male
  • Radiography
  • Sarcoidosis* / diagnostic imaging
  • Sarcoidosis* / drug therapy
  • Sarcoidosis* / etiology
  • Sarcoidosis* / pathology

Substances

  • Antimalarials
  • Glucocorticoids
  • Hydroxychloroquine
  • Chloroquine