Abstract
Drug administration during the last trimester of pregnancy may have adverse effects for the newborn.
Case report:
A hemolytic anemia occurred during the first hours of life in a full-term neonate whose mother had taken nitrofurantoin during the last month of pregnancy.
Conclusion:
The immature enzymatic systems of the neonate are exposed to this adverse effect and justify the recommendation not to prescribe nitrofurantoin at the end of pregnancy.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Adult
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Anemia, Hemolytic / chemically induced*
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Anti-Infective Agents, Urinary / administration & dosage
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Anti-Infective Agents, Urinary / adverse effects*
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Female
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Humans
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Infant, Newborn
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Infant, Newborn, Diseases / chemically induced*
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Male
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Maternal-Fetal Exchange
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Nitrofurantoin / administration & dosage
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Nitrofurantoin / adverse effects*
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Pregnancy
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Pregnancy Complications, Infectious / drug therapy
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Pregnancy Trimester, Third
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Urinary Tract Infections / drug therapy
Substances
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Anti-Infective Agents, Urinary
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Nitrofurantoin