Four steroidal alkaloids from the leaves of Buxus sempervirens

F Loru; D Duval; A Aumelas; F Akeb; D Guédon; R Guedj

doi:10.1016/s0031-9422(00)00036-4

Four steroidal alkaloids from the leaves of Buxus sempervirens

Phytochemistry. 2000 Aug;54(8):951-7. doi: 10.1016/s0031-9422(00)00036-4.

Authors

F Loru¹, D Duval, A Aumelas, F Akeb, D Guédon, R Guedj

Affiliation

¹ Laboratoire de Chimie Bio-Organique, UPRESA CNRS 6001, Faculté des Sciences, Université de Nice-Sophia Antipolis, Nice, France.

PMID: 11014296
DOI: 10.1016/s0031-9422(00)00036-4

Abstract

Four new steroidal alkaloids, N20-formylbuxaminol E [(20S)-16alpha-hydroxy-20-(formylamino)-3beta-(dimethylamino)-9,10 -seco-buxa-9(11),10(19)-diene] (1), O16-syringylbuxaminol E [(20S)-16alpha-syringoyl-3beta-(dimethylamino)-20-(amino)-9, 10-seco-buxa-9(11),10(19)-diene] (2), N20-acetylbuxamine G [(20S)-20-(acetylamino)-3beta-(methylamino)-9,10-seco-buxa-9(11),1 0(19)-diene] (3) and N20-acetylbuxamine E [(20S)-20-(acetylamino)-3beta-(dimethylamino)-9,10-seco-buxa-9(11) ,10(19)-diene] (4) were isolated from the leaves of Buxus sempervirens. Their structures were determined mainly on the basis of 2D NMR studies.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Alkaloids / chemistry
Alkaloids / isolation & purification*
Magnoliopsida / chemistry*
Molecular Structure
Plant Leaves / chemistry
Spectrum Analysis
Steroids / chemistry*

Substances

Alkaloids
Steroids