Abstract
Three sulfated alkene and alkanes-(R)-2,6-dimethylheptyl sulfate (1), 6-methylheptyl sulfate (2a), and (E)-5-octenyl sulfate (3a)-with cytotoxic activity in vitro, have been isolated from the Mediterranean ascidian Halocynthia papillosa. The structures of the new compounds 2a and 3a have been elucidated by spectroscopic analysis.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkanes / chemistry*
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Alkenes / chemistry*
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Animals
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Drug Screening Assays, Antitumor
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Heptanes / chemistry*
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Magnetic Resonance Spectroscopy
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Mediterranean Region
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Spectrometry, Mass, Fast Atom Bombardment
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Spectrophotometry, Infrared
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Sulfates / chemistry*
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Tumor Cells, Cultured
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Urochordata / chemistry*
Substances
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2,6-dimethylheptyl sulfate
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Alkanes
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Alkenes
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Heptanes
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Sulfates