Abstract
This study prospectively assessed subclinical cardiotoxicity in patients undergoing chemotherapy by using the Tei index combining systolic and diastolic time intervals. A significant difference in the Tei index was observed between patients who received a low dose and those who received a moderate to high dose of anthracycline antibiotic drugs. The Tei index is a sensitive, accurate, and easy approach for detecting subclinical anthracycline cardiotoxicity.
Publication types
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Comparative Study
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Evaluation Study
MeSH terms
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Antibiotics, Antineoplastic / adverse effects*
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Blood Flow Velocity / drug effects
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Child
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Echocardiography, Doppler
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Humans
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Mediastinal Neoplasms / drug therapy*
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Myocardial Contraction / drug effects
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Observer Variation
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Prognosis
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Prospective Studies
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Stroke Volume / drug effects
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Ventricular Dysfunction, Left / chemically induced
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Ventricular Dysfunction, Left / diagnostic imaging
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Ventricular Dysfunction, Left / physiopathology*
Substances
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Antibiotics, Antineoplastic