Abstract
An important aspect of structural genomics is connecting coordinate data with whole-genome information related to phylogenetic occurrence, protein function, gene expression, and protein-protein interactions. Integrative database analysis allows one to survey the 'finite parts list' of protein folds from many perspectives, highlighting certain folds and structural features that stand out in particular ways.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Computational Biology / methods*
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Computer Communication Networks*
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Databases as Topic*
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Gene Expression Profiling
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Genomics* / methods
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Internet
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Models, Molecular
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Phylogeny
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Protein Binding
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Protein Conformation
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Protein Folding
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Proteins / chemistry*
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Proteins / classification
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Proteins / genetics
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Proteins / metabolism
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Proteome
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Software
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Structure-Activity Relationship