Histopathology of the prefrontal cortex in major depression: what does it tell us about dysfunctional monoaminergic circuits?

Prog Brain Res. 2000:126:397-412. doi: 10.1016/S0079-6123(00)26026-3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Axons / ultrastructure
  • Cell Count
  • Cell Size
  • Cognition / physiology
  • Depressive Disorder, Major / metabolism
  • Depressive Disorder, Major / pathology*
  • Dopamine / physiology*
  • Emotions / physiology
  • Female
  • Glutamic Acid / physiology
  • Haplorhini
  • Humans
  • Locus Coeruleus / chemistry
  • Locus Coeruleus / pathology
  • Male
  • Motivation
  • Nerve Growth Factors / physiology
  • Nerve Tissue Proteins / analysis
  • Neural Pathways / physiopathology
  • Neuroglia / pathology
  • Neurons / chemistry
  • Neurons / pathology
  • Norepinephrine / physiology*
  • Prefrontal Cortex / metabolism
  • Prefrontal Cortex / pathology*
  • Raphe Nuclei / chemistry
  • Raphe Nuclei / pathology
  • Receptors, Adrenergic / drug effects
  • Receptors, Adrenergic / physiology
  • Receptors, Dopamine / drug effects
  • Receptors, Dopamine / physiology
  • Receptors, Glutamate / physiology
  • Receptors, Serotonin / drug effects
  • Receptors, Serotonin / physiology
  • Reward
  • Serotonin / physiology*
  • Tryptophan Hydroxylase / analysis
  • Tyrosine 3-Monooxygenase / analysis

Substances

  • Nerve Growth Factors
  • Nerve Tissue Proteins
  • Receptors, Adrenergic
  • Receptors, Dopamine
  • Receptors, Glutamate
  • Receptors, Serotonin
  • Serotonin
  • Glutamic Acid
  • Tyrosine 3-Monooxygenase
  • Tryptophan Hydroxylase
  • Dopamine
  • Norepinephrine