Abstract
A new flavan-3-ol glycoside, (-)-epicatechin-5-O-beta-D-glucosyl-3-benzoate (1), and two known compounds, (-)-epicatechin and (-)-epiafzelechin, were isolated from an EtOAc extract of Celastrus orbiculatus aerial parts that exhibited significant antioxidant effect in a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical assay. The structure of 1 was elucidated by spectroscopic analyses, and compound 1 and its aglycon, (-)-epicatechin-3-benzoate (2), were found to be moderately active as antioxidants in the DPPH assay.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antioxidants / chemistry
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Antioxidants / isolation & purification*
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Bepridil / analogs & derivatives*
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Bepridil / chemistry
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Biphenyl Compounds
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Catechin / chemistry
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Catechin / isolation & purification
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Flavonoids / chemistry
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Flavonoids / isolation & purification*
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Free Radical Scavengers / chemistry
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Free Radical Scavengers / isolation & purification*
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Free Radicals / chemistry
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Hydrolysis
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Picrates*
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Plants, Medicinal / chemistry*
Substances
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Antioxidants
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Biphenyl Compounds
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Flavonoids
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Free Radical Scavengers
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Free Radicals
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Picrates
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epiafzelechin
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Bepridil
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Catechin
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1,1-diphenyl-2-picrylhydrazyl