Abstract
The prognosis of patients with bladder cancer with pelvic lymph node metastasis is poor, and only 30% of them have been reported to achieve 5- and 10-year survival rates. Prognosis of the patients with pelvic lymph node metastasis larger than 5 cm (N3) is especially poor. and no patient has been reported to have survived more than 3 years. The authors report the successful treatment of two patients with pelvic N3 bladder cancer by internal iliac arterial infusion chemotherapy combined with whole-pelvis irradiation.
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage*
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Carboplatin / administration & dosage
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Carcinoma, Transitional Cell / drug therapy*
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Carcinoma, Transitional Cell / pathology
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Carcinoma, Transitional Cell / radiotherapy*
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Cisplatin / administration & dosage
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Doxorubicin / administration & dosage
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Doxorubicin / analogs & derivatives*
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Humans
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Iliac Artery
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Infusions, Intra-Arterial
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Lymphatic Metastasis
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Male
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Methotrexate / administration & dosage
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Neoplasm Staging
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Urinary Bladder Neoplasms / drug therapy*
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Urinary Bladder Neoplasms / pathology
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Urinary Bladder Neoplasms / radiotherapy*
Substances
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Doxorubicin
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Carboplatin
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pirarubicin
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Cisplatin
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Methotrexate