Conduction left-to-right and right-to-left across the crista terminalis

Am J Physiol Heart Circ Physiol. 2001 Apr;280(4):H1683-91. doi: 10.1152/ajpheart.2001.280.4.H1683.

Abstract

A line of block between the vena cava and the crista terminalis (CT) region is important for atrial flutter (AFL), but whether it is fixed or functional is controversial. To test the hypothesis that conduction across the CT normally occurs, but when block occurs in this region it is functional, we analyzed atrial activation during right and left atrial pacing (cycle lengths of 500--130 ms), AFL, and atrial fibrillation in 15 dogs with sterile pericarditis and 7 normal dogs. Electrograms from 396 right, left, and septal atrial sites were simultaneously recorded. Activation across the CT occurred during atrial pacing, AFL, and atrial fibrillation. Activation wave fronts from the right to the left atrium and vice versa traveled over several routes, including Bachmann's bundle and inferior to the inferior vena cava, as well as across the CT. In these models, there is no fixed conduction block across the CT, and when block in the CT region occurs, as during AFL, it is functional.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Atrial Fibrillation / physiopathology*
  • Atrial Flutter / physiopathology*
  • Atrial Function, Left / physiology
  • Atrial Function, Right / physiology
  • Coronary Circulation / physiology
  • Disease Models, Animal
  • Dogs
  • Electrophysiology / methods
  • Heart Conduction System / physiology*
  • Heart Conduction System / physiopathology
  • Pacemaker, Artificial
  • Pericarditis / physiopathology
  • Reference Values
  • Venae Cavae / physiology
  • Venae Cavae / physiopathology