Aspirin-induced activation of the NF-kappaB signaling pathway: a novel mechanism for aspirin-mediated apoptosis in colon cancer cells

FASEB J. 2001 May;15(7):1273-5.
No abstract available

MeSH terms

  • Active Transport, Cell Nucleus / physiology
  • Anti-Inflammatory Agents, Non-Steroidal / pharmacology
  • Antineoplastic Agents / pharmacology
  • Apoptosis / drug effects*
  • Aspirin / pharmacology*
  • Cell Nucleus / metabolism
  • Colon / drug effects
  • Colon / metabolism
  • Colonic Neoplasms / metabolism
  • Colonic Neoplasms / pathology*
  • DNA-Binding Proteins / metabolism
  • Humans
  • I-kappa B Proteins*
  • Intestinal Mucosa / drug effects
  • Intestinal Mucosa / metabolism
  • NF-KappaB Inhibitor alpha
  • NF-kappa B / metabolism*
  • Rectal Neoplasms / metabolism
  • Rectal Neoplasms / pathology
  • Signal Transduction / drug effects*
  • Signal Transduction / physiology
  • Tumor Cells, Cultured

Substances

  • Anti-Inflammatory Agents, Non-Steroidal
  • Antineoplastic Agents
  • DNA-Binding Proteins
  • I-kappa B Proteins
  • NF-kappa B
  • NFKBIA protein, human
  • NF-KappaB Inhibitor alpha
  • Aspirin