Anti-inflammatory mechanisms of methotrexate in rheumatoid arthritis

Ann Rheum Dis. 2001 Aug;60(8):729-35. doi: 10.1136/ard.60.8.729.
No abstract available

Publication types

  • Review

MeSH terms

  • Adenosine / metabolism
  • Animals
  • Antirheumatic Agents / metabolism
  • Antirheumatic Agents / pharmacology*
  • Apoptosis / drug effects
  • Arthritis, Rheumatoid / drug therapy*
  • Arthritis, Rheumatoid / metabolism
  • Arthritis, Rheumatoid / pathology
  • Cell Cycle / drug effects
  • Cyclic AMP / metabolism
  • Cyclooxygenase Inhibitors / pharmacology
  • Cytokines / drug effects
  • Cytokines / metabolism
  • Humans
  • Metalloendopeptidases / drug effects
  • Metalloendopeptidases / metabolism
  • Methotrexate / metabolism
  • Methotrexate / pharmacology*
  • Rats
  • fas Receptor / drug effects
  • fas Receptor / metabolism

Substances

  • Antirheumatic Agents
  • Cyclooxygenase Inhibitors
  • Cytokines
  • fas Receptor
  • Cyclic AMP
  • Metalloendopeptidases
  • Adenosine
  • Methotrexate