[Interest in treatment with subconjunctival clindamycin in toxoplasmic retinochoroiditis]

Tunis Med. 2001 Mar;79(3):157-60.
[Article in French]

Abstract

To demonstrate advantages of using subconjunctival injections of clindamycin in the treatment of toxoplasmic retinchoroiditis.

Methods: A prospective study was conducted in 13 patients with unilateral toxoplasmic retinochoroiditis. All cases were treated with subconjunctival injections of clindamycin in association with general corticosteroïds. Mean follow-up was 7.6 months.

Results: Subjective improvement of the visual acuity was obtained in 67% during the first week. Cicatrization was obtained in 1.4 months on average. Recurrences were developed in 15% of cases. Clindamycin did not produce any general side effects, however a conjunctival inflammation and keratitis were observed in one case caused by an error in concentration of clindamycin. Subconjunctival injections of clindamycin provide an interesting alternative in the choice of antitoxoplasmic ocular therapy.

Publication types

  • Clinical Trial
  • English Abstract

MeSH terms

  • Adolescent
  • Adult
  • Chorioretinitis / drug therapy*
  • Chorioretinitis / etiology*
  • Cicatrix
  • Clindamycin / administration & dosage*
  • Clindamycin / pharmacology*
  • Conjunctiva
  • Female
  • Humans
  • Inflammation
  • Keratitis / etiology
  • Male
  • Middle Aged
  • Prospective Studies
  • Recurrence
  • Toxoplasmosis, Ocular / complications*
  • Toxoplasmosis, Ocular / drug therapy*
  • Treatment Outcome

Substances

  • Clindamycin