Abstract
Plants and filamentous fungi share with mammals enzymes responsible for DNA methylation. In these organisms, DNA methylation is associated with gene silencing and transposon control. However, plants and fungi differ from mammals in the genomic distribution, sequence specificity, and heritability of methylation. We consider the role that transposons play in establishing methylation patterns and the epigenetic consequences of their perturbation.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
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Review
MeSH terms
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DNA Methylation*
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DNA Modification Methylases / metabolism
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DNA Transposable Elements*
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Fungi / enzymology
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Fungi / genetics*
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Gene Expression Regulation, Fungal*
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Gene Expression Regulation, Plant*
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Gene Silencing
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Genetic Variation
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Mutation
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Plants / enzymology
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Plants / genetics*
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RNA, Antisense / genetics
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RNA, Double-Stranded / metabolism
Substances
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DNA Transposable Elements
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RNA, Antisense
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RNA, Double-Stranded
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DNA Modification Methylases