RNA world: catalysis abets binding, but not vice versa

M Levy; A D Ellington

doi:10.1016/s0960-9822(01)00388-8

RNA world: catalysis abets binding, but not vice versa

Curr Biol. 2001 Aug 21;11(16):R665-7. doi: 10.1016/s0960-9822(01)00388-8.

Authors

M Levy¹, A D Ellington

Affiliation

¹ Department of Chemistry and Biochemistry, Institute for Cell and Molecular Biology, University of Texas at Austin, Austin, Texas 78712, USA.

PMID: 11525762
DOI: 10.1016/s0960-9822(01)00388-8

Abstract

The recent selection of a complex ribozyme capable of general polymerization on a template in trans has revealed how catalysts may have arisen from one another in the RNA world.

MeSH terms

Catalysis
DNA-Directed RNA Polymerases / metabolism
Evolution, Molecular
Ligands
Nucleic Acid Conformation
RNA / metabolism*
RNA, Catalytic / metabolism*

Substances

Ligands
RNA, Catalytic
RNA
DNA-Directed RNA Polymerases