Secondary amyloidosis in progressive systemic sclerosis

Clin Rheumatol. 2001;20(4):285-7. doi: 10.1007/s100670170048.

Abstract

Progressive systemic sclerosis (PSS) is a connective tissue disease that may affect many organs, including the kidneys. It is quite rare to see secondary amyloidosis due to PSS. We present a patient with a 9-year history of PSS who developed nephrotic syndrome, and whose renal biopsy was compatible with secondary amyloidosis. He died from massive upper gastrointestinal bleeding caused by oesophageal telangiectasia.

Publication types

  • Case Reports

MeSH terms

  • Amyloidosis / diagnosis
  • Amyloidosis / etiology*
  • Amyloidosis / therapy
  • Biopsy, Needle
  • Disease Progression
  • Esophageal and Gastric Varices / diagnosis
  • Esophageal and Gastric Varices / therapy
  • Fatal Outcome
  • Gastrointestinal Hemorrhage / diagnosis
  • Gastrointestinal Hemorrhage / therapy
  • Humans
  • Male
  • Middle Aged
  • Nephrotic Syndrome / diagnosis
  • Nephrotic Syndrome / etiology*
  • Nephrotic Syndrome / therapy
  • Scleroderma, Systemic / complications*
  • Scleroderma, Systemic / diagnosis
  • Scleroderma, Systemic / therapy
  • Severity of Illness Index