Evaluation of beta-cyclodextrin against natural infections of cryptosporidiosis in calves

Vet Parasitol. 2001 Nov 5;101(2):85-9. doi: 10.1016/s0304-4017(01)00505-2.

Abstract

The effectiveness of beta-cyclodextrin, excipient used in pharmaceutical industry, in the treatment of natural infection by Cryptosporidium parvum in suckling calves, was evaluated. Administration of the drug at a dose of 500 mg/kg body weight for 3 consecutive days from birth (prophylactically) or following confirmation of the infection (therapeutically) decreased the severity of diarrhoea and shortened the duration of oocyst shedding.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Suckling
  • Cattle
  • Cattle Diseases / drug therapy*
  • Cattle Diseases / parasitology
  • Cattle Diseases / prevention & control
  • Coccidiostats / pharmacology
  • Coccidiostats / therapeutic use
  • Cryptosporidiosis / drug therapy
  • Cryptosporidiosis / parasitology
  • Cryptosporidiosis / prevention & control
  • Cryptosporidiosis / veterinary*
  • Cryptosporidium parvum / drug effects*
  • Cryptosporidium parvum / growth & development
  • Cyclodextrins / pharmacology
  • Cyclodextrins / therapeutic use*
  • Diarrhea / drug therapy
  • Diarrhea / parasitology
  • Diarrhea / prevention & control
  • Diarrhea / veterinary*
  • Feces / parasitology
  • Female
  • Male
  • Parasitic Sensitivity Tests / veterinary
  • beta-Cyclodextrins*

Substances

  • Coccidiostats
  • Cyclodextrins
  • beta-Cyclodextrins
  • betadex