Skin test reactivity and cellular immune responses to Mycobacterium avium sensitin in AIDS patients at risk for disseminated M. avium infection

C F von Reyn; P L Williams; H M Lederman; J A McCutchan; S L Koletar; R L Murphy; S E Cohn; T Evans; A E Heald; D Colquhoun; E L Bassily; J S Currier

doi:10.1128/CDLI.8.6.1277-1278.2001

Skin test reactivity and cellular immune responses to Mycobacterium avium sensitin in AIDS patients at risk for disseminated M. avium infection

Clin Diagn Lab Immunol. 2001 Nov;8(6):1277-8. doi: 10.1128/CDLI.8.6.1277-1278.2001.

Authors

C F von Reyn¹, P L Williams, H M Lederman, J A McCutchan, S L Koletar, R L Murphy, S E Cohn, T Evans, A E Heald, D Colquhoun, E L Bassily, J S Currier

Affiliation

¹ Infectious Disease Section, Department of Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA. c.fordham.von.reyn@hitchcock.org

Abstract

Skin tests and lymphocyte proliferation assays (LPA) were performed with Mycobacterium avium sensitin on patients with AIDS. Among 139 subjects, 13% had positive skin test results and 32% had positive LPA results. The LPA may be a more sensitive indicator of prior M. avium infection in this population.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

AIDS-Related Opportunistic Infections / diagnosis*
AIDS-Related Opportunistic Infections / epidemiology
AIDS-Related Opportunistic Infections / immunology
Antigens / immunology*
Antigens, Bacterial / immunology
Cell Division / immunology
Humans
Lymphocytes / cytology
Lymphocytes / microbiology
Mycobacterium Infections / diagnosis*
Mycobacterium Infections / epidemiology
Mycobacterium Infections / immunology
Mycobacterium avium / immunology
Mycobacterium avium / isolation & purification*
Risk Factors
Sensitivity and Specificity
Skin Tests

Substances

Antigens
Antigens, Bacterial
sensitin