2-amidopyrroles and 2,5-diamidopyrroles as simple anion binding agents

P A Gale; S Camiolo; G J Tizzard; C P Chapman; M E Light; S J Coles; M B Hursthouse

doi:10.1021/jo016020g

2-amidopyrroles and 2,5-diamidopyrroles as simple anion binding agents

J Org Chem. 2001 Nov 16;66(23):7849-53. doi: 10.1021/jo016020g.

Authors

P A Gale¹, S Camiolo, G J Tizzard, C P Chapman, M E Light, S J Coles, M B Hursthouse

Affiliation

¹ Department of Chemistry, University of Southampton, Southampton, SO17 1BJ, UK. philip.gale@soton.ac.uk

PMID: 11701045
DOI: 10.1021/jo016020g

Abstract

Four new 2-amidopyrroles and 2,5-diamidopyrroles have been synthesized and their anion complexation properties investigated. The crystal structures of these receptors have been elucidated and reveal hydrogen bonding in the solid state leading to dimer and network formation. Selectivity for oxo-anions has been demonstrated by (1)H NMR titration techniques.