Two new sesquiterpene lactones from Montanoa tomentosa ssp. microcephala

Planta Med. 2001 Nov;67(8):774-6. doi: 10.1055/s-2001-18362.

Abstract

Two new sesquiterpene lactones: 8alpha-(4'-acetoxymethacryloyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alpha-olide (1) and 8alpha-(2'E)-(2'-acetoxymethyl-2'-butenoyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alphaolide (2), together with the known zoapatanolide A were isolated from the aerial parts of Montanoa tomentosa Cerv. in La Llave et Lex ssp. microcephala (Sch. Bip. In K. Koch) V.A. Funk (Asteraceae). The structures of all compounds were established on the basis of 1D, 2D NMR, and EIMS analysis.

MeSH terms

  • Abortifacient Agents, Nonsteroidal / chemistry
  • Abortifacient Agents, Nonsteroidal / isolation & purification
  • Asteraceae / chemistry*
  • Female
  • Humans
  • Lactones / chemistry
  • Lactones / isolation & purification*
  • Magnetic Resonance Spectroscopy
  • Medicine, Traditional
  • Mexico
  • Molecular Structure
  • Montanoa
  • Oxepins / chemistry
  • Oxepins / isolation & purification*
  • Sesquiterpenes / chemistry
  • Sesquiterpenes / isolation & purification*
  • Sesquiterpenes, Germacrane*

Substances

  • 8alpha-(2'E)-(2'-acetoxymethyl-2'-butenoyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alphaolide
  • 8alpha-(4'-acetoxymethacryloyloxy)-3alpha,9beta-dihydroxy-1(10)E,4Z,11(13)-germacratrien-12,6alpha-olide
  • Abortifacient Agents, Nonsteroidal
  • Lactones
  • Oxepins
  • Sesquiterpenes
  • Sesquiterpenes, Germacrane