Abstract
Recent studies on BAFF, a member of the tumor necrosis factor family, and the discovery of a new BAFF receptor have revealed that this ligand-receptor pair is essential for B-cell survival and differentiation, holding promise for a better understanding and treatment of some autoimmune diseases and lymphomas.
MeSH terms
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Animals
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B-Cell Activating Factor
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B-Lymphocytes / cytology
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Cell Survival / physiology
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Membrane Proteins / metabolism*
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Membrane Proteins / physiology
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Mice
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Tumor Necrosis Factor-alpha / metabolism*
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Tumor Necrosis Factor-alpha / physiology
Substances
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B-Cell Activating Factor
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Membrane Proteins
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Tnfsf13b protein, mouse
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Tumor Necrosis Factor-alpha