Tetra-trifluoroethoxyl zinc phthalocyanine: potential photosensitizer for use in the photodynamic therapy of cancer

J Photochem Photobiol B. 2001 Dec 1;65(1):35-8. doi: 10.1016/s1011-1344(01)00250-0.

Abstract

Tetra(trifluoroethoxyl) zinc phthalocyanine, which could be dissolved in most organic solvents, was synthesized. The compound displays a good photocytotoxicity on myeloma cells and Chinese hamster ovary cells in vitro in the presence of the emulsifying agent F68.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • CHO Cells
  • Cell Count
  • Cell Survival / drug effects
  • Cricetinae
  • Indoles / chemistry
  • Indoles / pharmacology*
  • Molecular Structure
  • Multiple Myeloma
  • Organometallic Compounds / chemistry
  • Organometallic Compounds / pharmacology*
  • Photochemotherapy*
  • Photosensitizing Agents / chemistry
  • Photosensitizing Agents / pharmacology*
  • Tumor Cells, Cultured

Substances

  • Indoles
  • Organometallic Compounds
  • Photosensitizing Agents