A model for odour thresholds

Chem Senses. 2002 Feb;27(2):95-104. doi: 10.1093/chemse/27.2.95.

Abstract

Odour detection thresholds, that we have previously obtained, have been analysed by a general equation for selective transport. It is shown that such selective transport can account for some 77% of the total effect. The remainder is due to a specific size effect, that might involve odour-binding proteins, and a specific effect for aldehydes and carboxylic acids. Our analysis raises the question of whether selective transport is physically separable from the specific effects of receptor activation. The model predicts a chemical cut-off in odour detection along any homologous series.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Aldehydes / chemistry
  • Animals
  • Carboxylic Acids / chemistry
  • Models, Chemical
  • Models, Theoretical
  • Odorants*
  • Sensory Thresholds / physiology*
  • Swine
  • Temperature

Substances

  • Aldehydes
  • Carboxylic Acids