fMRI/EEG in paroxysmal activity elicited by elimination of central vision and fixation

Neurology. 2002 Mar 26;58(6):976-9. doi: 10.1212/wnl.58.6.976.

Abstract

Using functional MRI (fMRI) with concurrent EEG monitoring the authors studied cortical activation associated with epileptiform discharges in three patients with fixation-off sensitivity. The EEG paroxysmal activity elicited by eliminating central vision correlated significantly with an increased blood oxygen level-dependent signal in the extrastriate cortex (Brodmann areas 19 and 37). fMRI provides a unique opportunity for localizing precisely the cortical areas generating paroxysmal activity in patients with fixation-off sensitivity.

MeSH terms

  • Adult
  • Cerebral Cortex / physiopathology*
  • Diagnostic Techniques, Ophthalmological
  • Electroencephalography / methods*
  • Epilepsy / diagnosis
  • Epilepsy / physiopathology*
  • Female
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Vision Disorders / diagnosis
  • Vision Disorders / physiopathology*
  • Vision Disparity / physiology*
  • Vision, Ocular