Electrophysiological correlates of visual categorization: evidence for cognitive dysfunctions in early Parkinson's disease

Brain Res Cogn Brain Res. 2002 Apr;13(2):153-8. doi: 10.1016/s0926-6410(01)00090-8.

Abstract

Our aim was to examine the electrophysiological correlates of perceptual categorization in Parkinson's disease (PD). We recorded visual event-related potentials (ERPs) in a natural scene categorization task in drug naive idiopathic PD patients and healthy control subjects. In the control group, there was a significant early difference (150-250 ms poststimulus) between ERPs elicited by pictures containing animals and scenes without animals. In spite of relatively preserved basic-level visual functions, this was not observable in the PD group. These results raise the possibility for striatal contributions to visual categorization and may provide a novel protocol for further clinical studies.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Attention / physiology
  • Cognition Disorders / etiology
  • Cognition Disorders / psychology*
  • Electroencephalography
  • Electrooculography
  • Electrophysiology
  • Evoked Potentials / physiology
  • Female
  • Humans
  • Male
  • Middle Aged
  • Parkinson Disease / complications
  • Parkinson Disease / psychology*
  • Psychiatric Status Rating Scales
  • Visual Perception / physiology*