Quality of virtual colonoscopy in patients who have undergone radiation therapy or surgery: how successful are we?

AJR Am J Roentgenol. 2002 May;178(5):1109-16. doi: 10.2214/ajr.178.5.1781109.

Abstract

Objective: In patients who have a history of abdominopelvic radiation, surgery, or both, conventional colonoscopy may fail to examine the entire colon. The purpose of this study is to assess whether high-quality virtual colonoscopy can be achieved in this patient population.

Materials and methods: After colonic cleansing, 61 patients (16 men and 45 women; mean age, 64 years; age range, 27-81 years) underwent 63 virtual colonoscopy examinations after using either single- or multidetector CT (slice thickness, 3.75-5.0 mm; table speed, 1.7-11.25 cm/sec; pitch, 1.5-3.0; and overlapped reconstructions, 1.95-2.5 cm) in supine and prone positions after IV administration of 1 mg of glucagon and rectal air insufflation. Conventional two-dimensional axial images were analyzed on a PACS (picture archiving and communication system) workstation. Two radiologists, who were unaware of patient history, independently evaluated the colonic distention on a 4-point scale (4 = optimal distention) and fluid retention on a 3-point scale (3 = no fluid) for all segments of the colon in patients who were imaged in both the supine and prone positions. Segmental and total average colon scores were calculated.

Results: Forty-one patients (65%; 43 examinations, 67%) underwent prior surgery, radiation, or both (surgery, n = 29; radiation, n = 3; both, n = 11). The average overall colonic distention and fluid retention for this group was 3.13 and 2.38, respectively, versus 3.24 and 2.3 in the control group (p = not significant).

Conclusion: High-quality examinations were achieved in patients who had previously undergone radiation, surgery, or both with no clinically significant difference in distention or fluid retention compared with the controls.

MeSH terms

  • Abdomen / radiation effects*
  • Abdomen / surgery*
  • Abdominal Neoplasms / radiotherapy*
  • Abdominal Neoplasms / surgery*
  • Adult
  • Aged
  • Aged, 80 and over
  • Colonic Neoplasms / diagnostic imaging*
  • Colonography, Computed Tomographic*
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted*
  • Male
  • Middle Aged
  • Pelvic Neoplasms / radiotherapy*
  • Pelvic Neoplasms / surgery*
  • Pelvis / radiation effects*
  • Pelvis / surgery*
  • Sensitivity and Specificity