Benign gastric carcinoid tumor with hypergastrinemia followed up for 12 years

Kimiyuki Hori; Hirokazu Fukui; Johji Imura; Takane Kojima; Mikio Fujita; Hitoski Kawamata; Tsutomu Chiba; Takahiro Fujimori

doi:10.1007/pl00011712

Benign gastric carcinoid tumor with hypergastrinemia followed up for 12 years

Gastric Cancer. 2000 Dec 27;3(3):161-164. doi: 10.1007/pl00011712.

Authors

Kimiyuki Hori¹, Hirokazu Fukui, Johji Imura, Takane Kojima, Mikio Fujita, Hitoski Kawamata, Tsutomu Chiba, Takahiro Fujimori

Affiliation

¹ Department of Pathology, Dokkyo University School of Medicine, 880 Kitakobayashi, Mibu, Shimotsuga, Tochigi 321-0293, Japan.

PMID: 11984731
DOI: 10.1007/pl00011712

Abstract

Gastric carcinoid tumors associated with chronic atrophic gastritis type A have been reported to show good prognosis, because invasion and metastasis are rare. We report a case of gastric carcinoid tumor associated with hypergastrinemia that showed no malignant changes for 12 years. A 15-year-old man with abdominal discomfort underwent endoscopic examination. A polypoid lesion was detected on the atrophic mucosa of the fundus, and was diagnosed as a carcinoid tumor. Serological examination revealed a high level of anti-parietal-cell antibody, suggesting that the patient had chronic atrophic gastritis type A. The tumor was treated by endoscopic mucosal resection. Follow-up examinations were performed for 12 years, but showed no recurrence. This case confirms that gastric carcinoid tumors associated with chronic atrophic gastritis type A may have a good prognosis.