Nickel-catalyzed cyclizations and couplings with vinylzirconium reagents

Org Lett. 2002 May 16;4(10):1743-5. doi: 10.1021/ol025812+.

Abstract

[reaction: see text] 1,3-Dienes were prepared by a variety of nickel-catalyzed couplings and cyclization processes. Intermolecular or partially intramolecular couplings of alkynes, vinylzirconium reagents, and either aldehydes or enones efficiently proceeded to generate a broad range of functionalized dienes.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Catalysis
  • Cyclization
  • Ethylenes / chemistry*
  • Indicators and Reagents
  • Nickel / chemistry*
  • Zirconium / chemistry*

Substances

  • Ethylenes
  • Indicators and Reagents
  • Nickel
  • Zirconium