Genotypic analysis by 27A DNA fingerprinting of Candida albicans strains isolated during an outbreak in a neonatal intensive care unit

Infect Control Hosp Epidemiol. 2002 May;23(5):281-4. doi: 10.1086/502052.

Abstract

We describe an outbreak of Candida albicans systemic infection involving five premature infants in a neonatal intensive care unit. Molecular and epidemiologic characterization of all C. albicans isolates was performed by DNA fingerprinting with the 27A probe. This genotypic analysis demonstrated that the isolates were identical, providing evidence for the circulation of a unique C. albicans strain.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Academic Medical Centers
  • Candida albicans / classification
  • Candida albicans / genetics*
  • Candidiasis / epidemiology
  • Candidiasis / microbiology*
  • Candidiasis / transmission
  • Cross Infection / epidemiology
  • Cross Infection / microbiology*
  • Cross Infection / transmission
  • DNA Fingerprinting / methods*
  • DNA, Fungal / genetics*
  • Disease Outbreaks / statistics & numerical data*
  • Genotype
  • Hospitals, Religious
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / epidemiology
  • Infant, Premature, Diseases / microbiology*
  • Infant, Very Low Birth Weight
  • Infection Control
  • Intensive Care Units, Neonatal*
  • Molecular Epidemiology
  • Retrospective Studies
  • Risk Factors
  • Rome / epidemiology

Substances

  • DNA, Fungal