Reconstruction of diaphragm using autologous fascia lata: an experimental study in dogs

Ann Thorac Surg. 2002 Jul;74(1):209-12. doi: 10.1016/s0003-4975(02)03635-4.

Abstract

Background: We investigated whether fascia lata is an appropriate material for reconstruction of the diaphragm.

Methods: A diaphragmatic defect (2 cm by 5 cm) was reconstructed with a patch of autologous fascia lata in the experimental group (n = 12) and with expanded polytetrafluoroethylene in the control group (n = 12). Maximal tensile strength at the sutured region was measured serially.

Results: The maximal tensile strength at the sutured region reconstructed with the fascia lata was 1.14 +/- 0.50 kgf 15 days and 2.04 +/- 0.94 kgf 30 days after operation. The values were higher than those of expanded polytetrafluoroethylene (p < 0.0001). These values of fascia lata were close to the original maximal tensile strength of the muscular region of the diaphragm (1.52 to 1.66 kgf).

Conclusions: Reconstruction of diaphragm using autologous fascia lata is safe, easy, and inexpensive, and provides smooth wound healing. The only disadvantage is the necessity of a femoral incision for harvest; nevertheless, it may be worthwhile to use fascia lata in clinical trials to further assess its suitability as a reconstruction material.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Animals
  • Diaphragm / surgery*
  • Dogs
  • Fascia Lata / transplantation*
  • Plastic Surgery Procedures*
  • Polytetrafluoroethylene / therapeutic use
  • Prostheses and Implants*
  • Tensile Strength
  • Transplantation, Autologous
  • Wound Healing

Substances

  • Polytetrafluoroethylene